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Sioux Falls
Home2 Suites By Hilton Sioux Falls Sanford Medical Center
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Home2 Suites By Hilton Sioux Falls Sanford Medical Center, Sioux Falls

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Up to 10% cheaper
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Check rooms and rates
From166US$ /night
Check-in
15Dec2025Select date
Check-out
16Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Perfect
8.6
9.3
/10
4.5
/5
“The hotel's location is perfect for easy access to Sanford Hospital and nearby amenities.”view full review

Home2 Suites By Hilton Sioux Falls Sanford Medical Center is a 3-star all-suite hotel featuring an indoor pool and fitness center. This pet-friendly hotel offers convenient access to Sanford Medical Center and includes a complimentary hot breakfast.

Rooms & Amenities

Rooms at Home2 Suites By Hilton are equipped with kitchens, featuring full-size refrigerators and microwaves, along with free WiFi. Guests can enjoy a flat-screen TV and a seating area in each suite, with accessible options available.

Dining & Nearby Options

A complimentary hot breakfast is served daily, and guests can also have groceries delivered directly to their suites. Nearby dining options include Azteca, Taco Bell, and Domino's Pizza, within 0.5 miles from the hotel.

Leisure & Business

Leisure amenities at this Sioux Falls hotel include an indoor saline swimming pool, hot tub, and a 24-hour fitness center. Business travelers benefit from a business center and meeting spaces totaling 950 square feet.

Location & Transportation

Home2 Suites By Hilton Sioux Falls is conveniently located near attractions such as Falls Park and Denny Sanford Premier Center, both within 6 minutes' drive. The hotel is 6 miles from Joe Foss Field Airport and offers free parking.

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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Studio Suite Non-Smoking
King Studio Suite Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
room details
Queen Studio Two Queen Beds Non-Smoking
Queen Studio Two Queen Beds Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
room details
King Studio Suite Hearing Access or Non-Smoking
King Studio Suite Hearing Access or Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
room details
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
room details
Click button to see more rooms
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Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences
Spacious Serenity
“The room was incredibly spacious, allowing me to relax and unwind comfortably during my stay.” view full review
Delicious Breakfast
“I loved the variety of breakfast items available; everything was delicious and set a great tone for the day.” view full review
Excellent Kitchen Area
“The kitchen area was very nice, providing convenience and comfort for anyone looking to make their own meals.” view full review
Safe & Comfortable
“I particularly appreciated the safety bars in the bathroom, which made my experience more secure while still feeling comfortable.” view full review

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
Show more

Location

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
City landmarks
Park
Falls Park
2.8 km
Zoo
Great Plains Zoo & Delbridge Museum of Natural History
2.1 km
Landmark
Michelangelo's David replica
1.3 km
Museum
The Pettigrew Home and Museum
1.8 km
Gallery
Rehfeld's Art and Framing
1.6 km
Park
Midco Aquatic Center
1.3 km
Church
St. Joseph Cathedral
2.4 km
Landmark
Lucky Lady Casino
1.1 km
Landmark
Spellerberg Park
1.0 km
Gallery
Eastbank Art Gallery
2.0 km
Church
First Lutheran Church
1.2 km
Landmark
The Blood Run Nature Area
2.3 km
Public Building
Old Courthouse Museum
2.7 km
Landmark
Downtown Sioux Falls
1.5 km
Park
McKennan Park
2.1 km
Landmark
SculptureWalk
1.5 km
Landmark
USS South Dakota
1.9 km
Landmark
Sioux Falls Bike Trail
2.2 km
Landmark
Fawick Park
1.8 km
Landmark
Drake Springs Family Aquatic Center
2.4 km
Landmark
Statue of David
1.8 km
Park
Terrace Park
2.4 km
Landmark
West Side City Casino
2.0 km
Landmark
Japanese Gardens
2.1 km
Gallery
Rug & Relic
2.0 km
Museum
Museum of Visual Materials
2.1 km
Park
Sherman Park
2.4 km
Landmark
Downtown
3.2 km
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
290 m
1001 SW Avenue
Sioux Falls Stadium
530 m
Restaurants
The Co-op of Sioux Falls
860 m
410 W 18th St
Azteca
1.1 km
811 S Minnesota Ave
Toppers Pizza
1.1 km
817 S Minnesota Ave
Taco John's
1.0 km
1100 S Minnesota Ave
Papa John's Pizza
1.1 km
711 S Minnesota Ave
Abelardo's Mexican Food
1.1 km
1200 S Minnesota Ave
Pho Quynh
960 m
1100 W 12th St
Getting around
City Centre
Sioux Falls10 min  ·  800 m
Airports
Sioux Falls Regional Airport (FSD)12 min  ·  7.9 km
Stronsay Airport (soy)130 min  ·  86.3 km
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
4
Number of rooms:
76

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Check-in
15Dec2025Select date
Check-out
16Dec2025Select date
Rooms and Guests2 Guests, 1 Room
  • Overview
  • Rooms
  • Price calendar
  • Facilities
  • Location
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